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Discovery of small molecule inhibitors of the HSP90-calcineurin-NFAT pathway against glioblastoma
Glioblastoma (GBM) is among the most common and malignant types of primary brain tumors in adult with a dismal prognosis. Although alkylating agents such as temozolomide are widely applied as the first-line treatment for GBM, they often cause chemoresistance and remain ineffective with recurrent GBM...
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| Veröffentlicht in: | Cell Chem Biol |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430684/ https://ncbi.nlm.nih.gov/pubmed/30639261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.11.009 |
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