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Activation of cryptic 3′ splice sites within introns of cellular genes following gene entrapment

Gene trap vectors developed for genome-wide mutagenesis can be used to study factors governing the expression of exons inserted throughout the genome. For example, entrapment vectors consisting of a partial 3′-terminal exon [i.e. a neomycin resistance gene (Neo), a poly(A) site, but no 3′ splice sit...

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Detaylı Bibliyografya
Asıl Yazarlar: Osipovich, Anna B., White-Grindley, Erica K., Hicks, Geoffrey G., Roshon, Michael J., Shaffer, Christian, Moore, Jason H., Ruley, H. Earl
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC419606/
https://ncbi.nlm.nih.gov/pubmed/15155860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh604
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