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Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene

BACKGROUND: Tagged sequence mutagenesis is a process for constructing libraries of sequenced insertion mutations in embryonic stem cells that can be transmitted into the mouse germline. To better predict the functional consequences of gene entrapment on cellular gene expression, the present study ch...

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Auteurs principaux: Roshon, Michael, DeGregori, James V, Ruley, H Earl
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC149352/
https://ncbi.nlm.nih.gov/pubmed/12546712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-4-2
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