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Post-entrapment genome engineering: First exon size does not affect the expression of fusion transcripts generated by gene entrapment
Gene trap mutagenesis in mouse embryonic stem cells has been widely used for genome-wide studies of mammalian gene function. However, while large numbers of genes can be disrupted, individual mutations may suffer from limitations due to the structure and/or placement of targeting vector. To extend t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC551569/ https://ncbi.nlm.nih.gov/pubmed/15741512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3258105 |
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