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Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells
BACKGROUND: Granzyme B (GrzB) is a serine proteinase expressed by memory T cells and NK cells. Methods to measure GrzB protein usually involve intracellular (flow cytometry) and extracellular (ELISA and ELISpot) assays. CD8 T cells are the main source of GrzB during immunological reactions, but acti...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195902/ https://ncbi.nlm.nih.gov/pubmed/25245659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0036-1 |
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