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Selective Expansion of Memory CD4(+) T cells By Mitogenic Human CD28 Generates Inflammatory Cytokines and Regulatory T cells
Co-stimulatory signals are important for development of effector and regulatory T cells. In this case, CD28 signaling is usually considered inert in the absence of signaling through the TCR. By contrast, mitogenic rat CD28 mAbs reportedly expand regulatory T cells without TCR stimulation. We found t...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735850/ https://ncbi.nlm.nih.gov/pubmed/18446791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737929 |
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