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Treatment-Naïve HIV-Infected Patients Have Fewer Gut-Homing β7 Memory CD4 T Cells than Healthy Controls

OBJECTIVES: The integrin α4β7 is the gut-homing receptor for lymphocytes. It also is an important co-receptor for human immunodeficiency virus (HIV) via glycoprotein (gp)120 binding. Depletion of gut cluster of differentiation (CD)4 T cells is linked to chronic inflammation in patients with HIV; how...

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Detalhes bibliográficos
Publicado no:South Med J
Main Authors: Fadul, Nada, Couturier, Jacob, Yu, Xiaoying, Kozinetz, Claudia, Arduino, Roberto, Lewis, Dorothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859930/
https://ncbi.nlm.nih.gov/pubmed/29100221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14423/SMJ.0000000000000730
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