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Efficient, Complete Deletion of Synaptic Proteins using CRISPR

One of the most powerful ways to test the function of a protein is to characterize the consequences of its deletion. In the past, this has involved inactivation of the gene by homologous recombination either in the germline or later through conditional deletion. RNA interference (RNAi) provides an a...

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Detalhes bibliográficos
Main Authors: Incontro, Salvatore, Asensio, Cedric S., Edwards, Robert H., Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195490/
https://ncbi.nlm.nih.gov/pubmed/25155957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.043
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