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Efficient, Complete Deletion of Synaptic Proteins using CRISPR

One of the most powerful ways to test the function of a protein is to characterize the consequences of its deletion. In the past, this has involved inactivation of the gene by homologous recombination either in the germline or later through conditional deletion. RNA interference (RNAi) provides an a...

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Autori principali: Incontro, Salvatore, Asensio, Cedric S., Edwards, Robert H., Nicoll, Roger A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195490/
https://ncbi.nlm.nih.gov/pubmed/25155957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.07.043
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