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Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP

The molecular mechanism underlying long-term potentiation (LTP) is critical for understanding learning and memory. CaMKII, a key kinase involved in LTP, is both necessary and sufficient for LTP induction. However, how CaMKII gives rise to LTP is currently unknown. Recent studies suggest that Rho GTP...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Herring, Bruce E., Nicoll, Roger A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776457/
https://ncbi.nlm.nih.gov/pubmed/26858404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600179113
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