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Kalirin and Trio: RhoGEFs in synaptic transmission, plasticity, and complex brain disorders

Changes in the actin cytoskeleton are a primary mechanism mediating the morphological and functional plasticity that underlies learning and memory. The synaptic RhoGEFs Kalirin and Trio have emerged as central regulators of actin dynamics at the synapse. The increased attention surrounding Kalirin a...

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Bibliographic Details
Published in:Trends Neurosci
Main Authors: Paskus, Jeremiah D., Herring, Bruce E., Roche, Katherine W.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321888/
https://ncbi.nlm.nih.gov/pubmed/32513570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2020.05.002
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