Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9

Recent genome-wide studies have revealed that the majority of the mouse genome is transcribed as non-coding RNAs (ncRNAs) and growing evidence supports the importance of ncRNAs in regulating gene expression and epigenetic processes. However, the low efficiency of conventional gene targeting strategi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Han, Jinxiong, Zhang, Jun, Chen, Li, Shen, Bin, Zhou, Jiankui, Hu, Bian, Du, Yinan, Tate, Peri H, Huang, Xingxu, Zhang, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Technical Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179957/
https://ncbi.nlm.nih.gov/pubmed/25137067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.29624
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados