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Computational design of receptors for an organophosphate surrogate of the nerve agent soman
We report the computational design of soluble protein receptors for pinacolyl methyl phosphonic acid (PMPA), the predominant hydrolytic product of the nerve agent soman. Using recently developed computational protein design techniques, the ligand-binding pockets of two periplasmic binding proteins,...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419530/ https://ncbi.nlm.nih.gov/pubmed/15148405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401309101 |
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