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Conversion of a maltose receptor into a zinc biosensor by computational design
We have demonstrated that it is possible to radically change the specificity of maltose binding protein by converting it into a zinc sensor using a rational design approach. In this new molecular sensor, zinc binding is transduced into a readily detected fluorescence signal by use of an engineered c...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33145/ https://ncbi.nlm.nih.gov/pubmed/11320244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091083898 |
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