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Conversion of a maltose receptor into a zinc biosensor by computational design

We have demonstrated that it is possible to radically change the specificity of maltose binding protein by converting it into a zinc sensor using a rational design approach. In this new molecular sensor, zinc binding is transduced into a readily detected fluorescence signal by use of an engineered c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Marvin, Jonathan S., Hellinga, Homme W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2001
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC33145/
https://ncbi.nlm.nih.gov/pubmed/11320244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091083898
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