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Computational design of receptors for an organophosphate surrogate of the nerve agent soman
We report the computational design of soluble protein receptors for pinacolyl methyl phosphonic acid (PMPA), the predominant hydrolytic product of the nerve agent soman. Using recently developed computational protein design techniques, the ligand-binding pockets of two periplasmic binding proteins,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419530/ https://ncbi.nlm.nih.gov/pubmed/15148405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401309101 |
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