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Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells

Wnt-targeted gene therapy has been proposed as a treatment for human colorectal cancer (CRC). The Cre-Lox system consists of methodology for enhancing targeted expression from tissue-specific or cancer-specific promoters. We analyzed the efficiency of Wnt-specific promoters as drivers of the Cre-med...

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Autors principals: Bordonaro, Michael, Lazarova, Darina L., Sartorelli, Alan C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC419474/
https://ncbi.nlm.nih.gov/pubmed/15141037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh596
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