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Amlexanox and UPF1 Modulate Wnt Signaling and Apoptosis in HCT-116 Colorectal Cancer Cells

Deregulated Wnt signaling initiates most cases of colorectal cancer (CRC). Butyrate, a product of dietary fiber, hyperactivates Wnt signaling, resulting in induction of CRC cell apoptosis, which may in part explain the protective action of fiber. Nonsense mediated decay (NMD) of mRNAs containing pre...

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Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Bordonaro, Michael, Lazarova, Darina
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360298/
https://ncbi.nlm.nih.gov/pubmed/30719122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.28331
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