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Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells

BACKGROUND: The Wnt signaling pathway, mediated through active beta-catenin, is responsible for initiating the majority of cases of human colorectal cancer (CRC), and we have previously shown that hyperactivation of this pathway by histone deacetylase inhibitors (HDACis), such as butyrate, can induc...

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Podrobná bibliografie
Vydáno v:JMIR Res Protoc
Hlavní autoři: Bordonaro, Michael, Lazarova, Darina Lazarova
Médium: Artigo
Jazyk:Inglês
Vydáno: JMIR Publications Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884266/
https://ncbi.nlm.nih.gov/pubmed/27177606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/resprot.5495
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