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Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells

BACKGROUND: The Wnt signaling pathway, mediated through active beta-catenin, is responsible for initiating the majority of cases of human colorectal cancer (CRC), and we have previously shown that hyperactivation of this pathway by histone deacetylase inhibitors (HDACis), such as butyrate, can induc...

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Bibliografiske detaljer
Udgivet i:JMIR Res Protoc
Main Authors: Bordonaro, Michael, Lazarova, Darina Lazarova
Format: Artigo
Sprog:Inglês
Udgivet: JMIR Publications Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884266/
https://ncbi.nlm.nih.gov/pubmed/27177606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/resprot.5495
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