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Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells

BACKGROUND: The Wnt signaling pathway, mediated through active beta-catenin, is responsible for initiating the majority of cases of human colorectal cancer (CRC), and we have previously shown that hyperactivation of this pathway by histone deacetylase inhibitors (HDACis), such as butyrate, can induc...

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Detalhes bibliográficos
Publicado no:JMIR Res Protoc
Main Authors: Bordonaro, Michael, Lazarova, Darina Lazarova
Formato: Artigo
Idioma:Inglês
Publicado em: JMIR Publications Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884266/
https://ncbi.nlm.nih.gov/pubmed/27177606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/resprot.5495
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