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p300 Knockout Promotes Butyrate Resistance

Dietary fiber is linked to a reduced risk of colorectal cancer (CRC), and this protective activity is likely due to its fermentation product, butyrate. Dependent upon the hyperactivation of Wnt signaling, butyrate represses CRC cell growth and induces apoptosis. However, resistance to butyrate activ...

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Detalles Bibliográficos
Publicado en:J Cancer
Main Authors: Lazarova, Darina L., Bordonaro, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687153/
https://ncbi.nlm.nih.gov/pubmed/29151923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21145
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