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Vimentin, colon cancer progression and resistance to butyrate and other HDACis

Dietary fibre protects against colorectal cancer (CRC) most likely through the activity of its fermentation product, butyrate. Butyrate functions as a histone deacetylase inhibitor (HDACi) that hyperactivates Wnt signalling and induces apoptosis of CRC cells. However, individuals who consume a high‐...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lazarova, Darina L., Bordonaro, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882977/
https://ncbi.nlm.nih.gov/pubmed/27072512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12850
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