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Hypothesis: Obesity Is Associated with a Lower Mutation Threshold in Colon Cancer
Neoplastic progression requires accumulation of several mutations (mutation threshold). We hypothesize that obesity raises the risk of microsatellite stable (MSS) colon cancer (CC) at least in part by decreasing the mutation threshold. Thus, we posit that obese patients require fewer mutations, part...
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| Publicado no: | J Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532979/ https://ncbi.nlm.nih.gov/pubmed/26284133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.12352 |
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