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Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells
BACKGROUND: The Wnt signaling pathway, mediated through active beta-catenin, is responsible for initiating the majority of cases of human colorectal cancer (CRC), and we have previously shown that hyperactivation of this pathway by histone deacetylase inhibitors (HDACis), such as butyrate, can induc...
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| Publicado en: | JMIR Res Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
JMIR Publications Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884266/ https://ncbi.nlm.nih.gov/pubmed/27177606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2196/resprot.5495 |
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