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The Activation of Beta-Catenin by Wnt Signaling Mediates the Effects of Histone Deacetylase Inhibitors
Most colorectal carcinomas (CRCs) exhibit constitutively active Wnt signaling. We have reported that (a) the histone deacetylase inhibitor (HDACi)() sodium butyrate (NaB) modulates the canonical Wnt transcriptional activity of CRC cells in vitro and (b) a linear relationship exists between the incre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919021/ https://ncbi.nlm.nih.gov/pubmed/17359971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.02.008 |
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