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The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML

NPM1 mutations represent frequent genetic alterations in patients with acute myeloid leukemia (AML) associated with a favorable prognosis. Different types of NPM1 mutations have been described. The purpose of our study was to evaluate the relevance of different NPM1 mutation types with regard to cli...

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Autors principals: Pastore, Friederike, Greif, Philipp A., Schneider, Stephanie, Ksienzyk, Bianka, Mellert, Gudrun, Zellmeier, Evelyn, Braess, Jan, Sauerland, Cristina M., Heinecke, Achim, Krug, Utz, Berdel, Wolfgang E., Buechner, Thomas, Woermann, Bernhard, Hiddemann, Wolfgang, Spiekermann, Karsten
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192029/
https://ncbi.nlm.nih.gov/pubmed/25299584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109759
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