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RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP
Various helicases and single-stranded DNA (ssDNA) binding proteins are known to destabilize G-quadruplex (GQ) structures, which otherwise result in genomic instability. Bulk biochemical studies have shown that Bloom helicase (BLM) unfolds both intermolecular and intramolecular GQ in the presence of...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191421/ https://ncbi.nlm.nih.gov/pubmed/25245947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku856 |
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