Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release

In Alzheimer’s disease, cytochrome c-dependent apoptosis is a crucial pathway in neuronal cell death. Although beta-amyloid (Aβ) oligomers are known to be the neurotoxins responsible for neuronal cell death, the underlying mechanisms remain largely elusive. Here, we report that the oligomeric form o...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kim, Jaewook, Yang, Yoosoo, Song, Seung Soo, Na, Jung-Hyun, Oh, Kyoung Joon, Jeong, Cherlhyun, Yu, Yeon Gyu, Shin, Yeon-Kyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
Soggetti:
Membranes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190645/
https://ncbi.nlm.nih.gov/pubmed/25296312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.074
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi