Organization of the Mitochondrial Apoptotic BAK Pore: OLIGOMERIZATION OF THE BAK HOMODIMERS

The multidomain pro-apoptotic Bcl-2 family proteins BAK and BAX are believed to form large oligomeric pores in the mitochondrial outer membrane during apoptosis. Formation of these pores results in the release of apoptotic factors including cytochrome c from the intermembrane space into the cytoplas...

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Detalhes bibliográficos
Main Authors: Aluvila, Sreevidya, Mandal, Tirtha, Hustedt, Eric, Fajer, Peter, Choe, Jun Yong, Oh, Kyoung Joon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908389/
https://ncbi.nlm.nih.gov/pubmed/24337568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526806
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