Organization of the Mitochondrial Apoptotic BAK Pore: OLIGOMERIZATION OF THE BAK HOMODIMERS

The multidomain pro-apoptotic Bcl-2 family proteins BAK and BAX are believed to form large oligomeric pores in the mitochondrial outer membrane during apoptosis. Formation of these pores results in the release of apoptotic factors including cytochrome c from the intermembrane space into the cytoplas...

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Bibliographische Detailangaben
Hauptverfasser: Aluvila, Sreevidya, Mandal, Tirtha, Hustedt, Eric, Fajer, Peter, Choe, Jun Yong, Oh, Kyoung Joon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908389/
https://ncbi.nlm.nih.gov/pubmed/24337568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.526806
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