Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release

In Alzheimer’s disease, cytochrome c-dependent apoptosis is a crucial pathway in neuronal cell death. Although beta-amyloid (Aβ) oligomers are known to be the neurotoxins responsible for neuronal cell death, the underlying mechanisms remain largely elusive. Here, we report that the oligomeric form o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Jaewook, Yang, Yoosoo, Song, Seung Soo, Na, Jung-Hyun, Oh, Kyoung Joon, Jeong, Cherlhyun, Yu, Yeon Gyu, Shin, Yeon-Kyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2014
Pynciau:
Membranes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190645/
https://ncbi.nlm.nih.gov/pubmed/25296312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.074
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