Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release

In Alzheimer’s disease, cytochrome c-dependent apoptosis is a crucial pathway in neuronal cell death. Although beta-amyloid (Aβ) oligomers are known to be the neurotoxins responsible for neuronal cell death, the underlying mechanisms remain largely elusive. Here, we report that the oligomeric form o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Jaewook, Yang, Yoosoo, Song, Seung Soo, Na, Jung-Hyun, Oh, Kyoung Joon, Jeong, Cherlhyun, Yu, Yeon Gyu, Shin, Yeon-Kyun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2014
Gaiak:
Membranes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190645/
https://ncbi.nlm.nih.gov/pubmed/25296312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.074
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