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Beta-Amyloid Oligomers Activate Apoptotic BAK Pore for Cytochrome c Release
In Alzheimer’s disease, cytochrome c-dependent apoptosis is a crucial pathway in neuronal cell death. Although beta-amyloid (Aβ) oligomers are known to be the neurotoxins responsible for neuronal cell death, the underlying mechanisms remain largely elusive. Here, we report that the oligomeric form o...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190645/ https://ncbi.nlm.nih.gov/pubmed/25296312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.074 |
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