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ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children
AIM: Large interindividual variability in morphine pharmacokinetics could contribute to variability in morphine analgesia and adverse events. METHODS: Influence of weight, genetic polymorphisms, race and sex on morphine clearance and metabolite formation from 220 children undergoing outpatient adeno...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190075/ https://ncbi.nlm.nih.gov/pubmed/25155932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.99 |
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