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OCT1 genetic variants influence the pharmacokinetics of morphine in children

AIM: Large interindividual variability in morphine disposition could contribute to unpredictable variability in morphine analgesia and adverse events. Caucasian children have more adverse effects and slower morphine clearance than African–American children. To study variations in intravenous morphin...

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Detalhes bibliográficos
Main Authors: Fukuda, Tsuyoshi, Chidambaran, Vidya, Mizuno, Tomoyuki, Venkatasubramanian, Raja, Ngamprasertwong, Pornswan, Olbrecht, Vanessa, Esslinger, Hope R, Vinks, Alexander A, Sadhasivam, Senthilkumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116670/
https://ncbi.nlm.nih.gov/pubmed/23859569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.94
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