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POPULATION PHARMACOKINETIC-PHARMACODYNAMIC MODELING AND DOSING SIMULATION OF PROPOFOL MAINTENANCE ANESTHESIA IN SEVERELY OBESE ADOLESCENTS
BACKGROUND: Optimal dosing of propofol to maintain appropriate anesthetic depth is challenging in severely obese (SO) adolescents. We previously reported that total body weight (TBW) is predictive of propofol clearance. This study was aimed at characterizing pharmacokinetics (PK) and pharmacodynamic...
שמור ב:
| הוצא לאור ב: | Paediatr Anaesth |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516654/ https://ncbi.nlm.nih.gov/pubmed/25975390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pan.12684 |
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