OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children

AIM: Large interindividual variability in morphine pharmacokinetics (PK) could contribute to variability in morphine analgesia and adverse events. Respiratory depression (RD) and postoperative nausea and vomiting (PONV) are significant adverse drug response of intravenous morphine in the perioperati...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Balyan, Rajiv, Zhang, Xue, Chidambaran, Vidya, Martin, Lisa J, Mizuno, Tomoyuki, Fukuda, Tsuyoshi, Vinks, Alexander A, Sadhasivam, Senthilkumar
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591462/
https://ncbi.nlm.nih.gov/pubmed/28470102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0002
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