OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children

AIM: Large interindividual variability in morphine pharmacokinetics (PK) could contribute to variability in morphine analgesia and adverse events. Respiratory depression (RD) and postoperative nausea and vomiting (PONV) are significant adverse drug response of intravenous morphine in the perioperati...

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Publicado en:Pharmacogenomics
Autores principales: Balyan, Rajiv, Zhang, Xue, Chidambaran, Vidya, Martin, Lisa J, Mizuno, Tomoyuki, Fukuda, Tsuyoshi, Vinks, Alexander A, Sadhasivam, Senthilkumar
Formato: Artigo
Lenguaje:Inglês
Publicado: Future Medicine Ltd 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591462/
https://ncbi.nlm.nih.gov/pubmed/28470102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0002
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