Novel Associations between FAAH Genetic Variants and Postoperative Central Opioid related Adverse Effects

Opioid effects are potentiated by cannabinoid agonists including anandamide, an endocannabinoid. Inter-individual variability in responses to opioids is a major clinical problem. Multiple deaths and anoxic brain injuries occur every year in due to opioid induced respiratory depression in surgical pa...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Sadhasivam, Senthilkumar, Zhang, Xue, Chidambaran, Vidya, Mavi, Jagroop, Pilipenko, Valentina, Mersha, Tesfaye B., Meller, Jaroslaw, Kaufman, Kenneth M., Martin, Lisa J., McAuliffe, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492912/
https://ncbi.nlm.nih.gov/pubmed/25558980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2014.79
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