Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer

Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and various molecules have been developed in an attempt to...

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Bibliografski detalji
Glavni autori: Simmons, Suzanne C., Jämsä, Hannaleena, Silva, Dilson, Cortez, Celia M., McKenzie, Edward A., Bitu, Carolina C., Salo, Sirpa, Nurmenniemi, Sini, Nyberg, Pia, Risteli, Juha, deAlmeida, Carlos E. B., Brenchley, Paul E. C., Salo, Tuula, Missailidis, Sotiris
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://ncbi.nlm.nih.gov/pubmed/25295847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096846
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