Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer

Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and various molecules have been developed in an attempt to...

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Bibliografische gegevens
Hoofdauteurs: Simmons, Suzanne C., Jämsä, Hannaleena, Silva, Dilson, Cortez, Celia M., McKenzie, Edward A., Bitu, Carolina C., Salo, Sirpa, Nurmenniemi, Sini, Nyberg, Pia, Risteli, Juha, deAlmeida, Carlos E. B., Brenchley, Paul E. C., Salo, Tuula, Missailidis, Sotiris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://ncbi.nlm.nih.gov/pubmed/25295847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096846
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