Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer

Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and various molecules have been developed in an attempt to...

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Bibliografiset tiedot
Päätekijät: Simmons, Suzanne C., Jämsä, Hannaleena, Silva, Dilson, Cortez, Celia M., McKenzie, Edward A., Bitu, Carolina C., Salo, Sirpa, Nurmenniemi, Sini, Nyberg, Pia, Risteli, Juha, deAlmeida, Carlos E. B., Brenchley, Paul E. C., Salo, Tuula, Missailidis, Sotiris
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://ncbi.nlm.nih.gov/pubmed/25295847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096846
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