Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer

Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and various molecules have been developed in an attempt to...

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Detalhes bibliográficos
Main Authors: Simmons, Suzanne C., Jämsä, Hannaleena, Silva, Dilson, Cortez, Celia M., McKenzie, Edward A., Bitu, Carolina C., Salo, Sirpa, Nurmenniemi, Sini, Nyberg, Pia, Risteli, Juha, deAlmeida, Carlos E. B., Brenchley, Paul E. C., Salo, Tuula, Missailidis, Sotiris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://ncbi.nlm.nih.gov/pubmed/25295847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096846
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