Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis

BACKGROUND: The maintenance of stem cell pluripotency is controlled by a core cluster of transcription factors, NANOG, OCT4 and SOX2 – genes that jointly regulate each other’s expression. The expression of some of these genes, especially of Nanog, is heterogeneous in a population of undifferentiated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lakatos, Dora, Travis, Emily D, Pierson, Kelsey E, Vivian, Jay L, Czirok, Andras
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189679/
https://ncbi.nlm.nih.gov/pubmed/25267505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0112-4
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