Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

Embryonic stem cell (ESC) self-renewal efficiency is determined by the level of Nanog expression. However, the mechanisms by which Nanog functions remain unclear, and in particular, direct Nanog target genes are uncharacterized. Here we investigate ESCs expressing different Nanog levels and Nanog(−/...

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Bibliographische Detailangaben
Hauptverfasser: Festuccia, Nicola, Osorno, Rodrigo, Halbritter, Florian, Karwacki-Neisius, Violetta, Navarro, Pablo, Colby, Douglas, Wong, Frederick, Yates, Adam, Tomlinson, Simon R., Chambers, Ian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473361/
https://ncbi.nlm.nih.gov/pubmed/23040477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.08.002
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