Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

The transcription factors (TFs) Nanog and Esrrb play important roles in embryonic stem cells (ESCs) and during primordial germ-cell (PGC) development. Esrrb is a positively regulated direct target of NANOG in ESCs that can substitute qualitatively for Nanog function in ESCs. Whether this functional...

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Publicat a:Cell Rep
Autors principals: Zhang, Man, Leitch, Harry G., Tang, Walfred W.C., Festuccia, Nicola, Hall-Ponsele, Elisa, Nichols, Jennifer, Surani, M. Azim, Smith, Austin, Chambers, Ian
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775501/
https://ncbi.nlm.nih.gov/pubmed/29320730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.060
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