Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

Embryonic stem cell (ESC) self-renewal efficiency is determined by the level of Nanog expression. However, the mechanisms by which Nanog functions remain unclear, and in particular, direct Nanog target genes are uncharacterized. Here we investigate ESCs expressing different Nanog levels and Nanog(−/...

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Main Authors: Festuccia, Nicola, Osorno, Rodrigo, Halbritter, Florian, Karwacki-Neisius, Violetta, Navarro, Pablo, Colby, Douglas, Wong, Frederick, Yates, Adam, Tomlinson, Simon R., Chambers, Ian
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473361/
https://ncbi.nlm.nih.gov/pubmed/23040477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.08.002
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