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Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis
BACKGROUND: The maintenance of stem cell pluripotency is controlled by a core cluster of transcription factors, NANOG, OCT4 and SOX2 – genes that jointly regulate each other’s expression. The expression of some of these genes, especially of Nanog, is heterogeneous in a population of undifferentiated...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4189679/ https://ncbi.nlm.nih.gov/pubmed/25267505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0112-4 |
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