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FGF mediated MAPK and PI3K/Akt Signals make distinct contributions to pluripotency and the establishment of Neural Crest

Early vertebrate embryos possess cells with the potential to generate all embryonic cell types. While this pluripotency is progressively lost as cells become lineage restricted, Neural Crest cells retain broad developmental potential. Here, we provide novel insights into signals essential for both p...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Geary, Lauren, LaBonne, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790379/
https://ncbi.nlm.nih.gov/pubmed/29350613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33845
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