Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β-Secretase

Lignende værker

• Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β-Secretase
  af: Arghya Barman, et al.
  Udgivet: (2014-01-01)
• Loss of Cleavage at β′-Site Contributes to Apparent Increase in β-Amyloid Peptide (Aβ) Secretion by β-Secretase (BACE1)-Glycosylphosphatidylinositol (GPI) Processing of Amyloid Precursor Protein
  af: Vetrivel, Kulandaivelu S., et al.
  Udgivet: (2011)
• Computational design of catalytic dyads and oxyanion holes for ester hydrolysis
  af: Richter, Florian, et al.
  Udgivet: (2012)
• Substrate docking to γ-secretase allows access of γ-secretase modulators to an allosteric site
  af: Uemura, Kengo, et al.
  Udgivet: (2010)
• Klotho is a substrate for α-, β- and γ-secretase
  af: Bloch, Laura, et al.
  Udgivet: (2009)