The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk

OBJECTIVES: Recently, 2 independent studies reported that a rare missense variant, rs75932628 (R47H), in exon 2 of the gene encoding the “triggering receptor expressed on myeloid cells 2” (TREM2) significantly increases the risk of Alzheimer disease (AD) with an effect size comparable to that of the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hooli, Basavaraj V., Parrado, Antonio R., Mullin, Kristina, Yip, Wai-Ki, Liu, Tian, Roehr, Johannes T., Qiao, Dandi, Jessen, Frank, Peters, Oliver, Becker, Tim, Ramirez, Alfredo, Lange, Christoph, Bertram, Lars, Tanzi, Rudolph E.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189101/
https://ncbi.nlm.nih.gov/pubmed/25186855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000855
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados