The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk

OBJECTIVES: Recently, 2 independent studies reported that a rare missense variant, rs75932628 (R47H), in exon 2 of the gene encoding the “triggering receptor expressed on myeloid cells 2” (TREM2) significantly increases the risk of Alzheimer disease (AD) with an effect size comparable to that of the...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hooli, Basavaraj V., Parrado, Antonio R., Mullin, Kristina, Yip, Wai-Ki, Liu, Tian, Roehr, Johannes T., Qiao, Dandi, Jessen, Frank, Peters, Oliver, Becker, Tim, Ramirez, Alfredo, Lange, Christoph, Bertram, Lars, Tanzi, Rudolph E.
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2014
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189101/
https://ncbi.nlm.nih.gov/pubmed/25186855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000855
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы