Family-based Association Analyses of Imputed Genotypes Reveal Genome-Wide Significant Association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3

The genetic basis of Alzheimer's disease (AD) is complex and heterogeneous. Over 200 highly penetrant pathogenic variants in the genes APP, PSEN1 and PSEN2 cause a subset of early-onset familial Alzheimer's disease (EOFAD). On the other hand, susceptibility to late-onset forms of AD (LOAD)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Herold, Christine, Hooli, Basavaraj V., Mullin, Kristina, Liu, Tian, Roehr, Johannes T, Mattheisen, Manuel, Parrado, Antonio R., Bertram, Lars, Lange, Christoph, Tanzi, Rudolph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970971/
https://ncbi.nlm.nih.gov/pubmed/26830138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.218
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados