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Repair kinetics of acrolein– and (E)-4-hydroxy-2-nonenal–derived DNA adducts in human colon cell extracts

ω-3 and ω-6 Polyunsaturated fatty acids (PUFAs) play a role in the pathogenesis of colon cancer. Upon oxidation, PUFAs generate α,β-unsaturated aldehydes or enals, such as acrolein (Acr) and (E)-4-hydroxy-2-nonenal (HNE), which can form cyclic adducts of deoxyguanosine (Acr-dG and HNE-dG, respective...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Choudhury, Sujata, Dyba, Marcin, Pan, Jishen, Roy, Rabindra, Chung, Fung-Lung
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188536/
https://ncbi.nlm.nih.gov/pubmed/24113140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2013.09.004
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