High-throughput, Quantitative Analysis of Acrolein-derived DNA Adducts in Human Oral Cells by Immunohistochemistry

Acrolein (Acr) is a ubiquitous environmental pollutant as well as an endogenous compound. Acrolein-derived 1,N(2)-propanodeoxyguanosines (Acr-dG) are exocyclic DNA adducts formed following exposure to cigarette smoke or from lipid peroxidation. Acr-dG is mutagenic and potentially carcinogenic and ma...

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Detalhes bibliográficos
Main Authors: Greenspan, Emily J., Lee, Hanjoo, Dyba, Marcin, Pan, Jishen, Mekambi, Kepher, Johnson, Tierra, Blancato, Jan, Mueller, Susette, Berry, Deborah L., Chung, Fung-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524569/
https://ncbi.nlm.nih.gov/pubmed/22899861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155412459759
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